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respiratoria

Enfermedades Respiratorias

Líneas de investigación

Síndrome de Apneas-Hipopneas del Sueño (SAHS) y tratamiento telemático
Síndrome de hipoventilación y obesidad.
Síndrome de Hipoventilación-Obesidad (SHO): tratamiento con dispositivos automáticos
Síndrome de Hipoventilación-Obesidad (SHO): tratamiento y manejo en pacientes ambulatorios
Síndrome de Hipoventilación-Obesidad (SHO): tratamiento y manejo en pacientes post-agudos
Tabaquismo y Enfermedad Pulmonar Obstructiva Crónica (EPOC)
Tabaquismo y EPOC.
Tratamiento con ventilación no invasiva en agudos y crónicos
Síndrome de Apneas-Hipopneas del Sueño (SAHS) y cáncer
Síndrome de Apneas-Hipopneas del Sueño (SAHS) y enfermedad cardiovascular

Proyectos de investigación

RESPIRATORY SUPPORT IN COPD PATIENTS AFTER ACUTE EXACERBATION WITH MONITORING THE QUALITY OF SUPPORT
PRESIÓN POSITIVA EN LA VÍA AEREA EN EL SHO
A EROPEAN MULTICENTER LONG-TERM OBSERVATIONAL COHORT (ESADA - EUROPEAN SLEEP APNEA DATABASE)
A multi-centre, randomized study to assess the effects of adaptive servo-ventilation (ASV) on survival and frequency of cardiovascular (CV) Hospital admissions in patients with Heart Failure (HF) and sleep apnea (SA). The ADVENT-HF trial
Integrating molecular, genomic, morphology and environmental features to improve precision diagnosis and treatment in interstitial lung diseases (PRECISION-ILD)
Impact of Sleep-disordered Breathing Management in Systemic Hypertension Control: METASLEEP project.
VALIDEZ Y COSTE-EFECTIVIDAD DE LA POLIGRAFÍA RESPIRATORIA DOMICILIARIA PARA EL DIAGNÓSTICO DE LA APNEA OBSTRUCTIVA DEL SUEÑO EN EL NIÑO (DINISAS)
LONG-TERM EVOLUTION OF WEIGHT IN OHS. A META-ANALYSIS.
SYSTEMATIC REVIEW AND META-ANALYSIS OF RCTs COMPARING PRIMARY CARE VS SLEEP CENTRE MANAGMENT OF PATIENTS WITH SUSPECTED OSA
EFECTIVIDAD A MEDIO Y LARGO PLAZO DE LA PRESIÓN POSTIVA EN LAS VÍAS AREAS EN EL SÍNDROME DE HIPOVENTILACIÓN OBSIDAD (SHO) DESPUÉS DE UNA AGUDIZACIÓN DE LA INSUFICIENCIA RESPIRATORIA HIPERCÁPNICA
GLOBAL SELF-MANAGMENT TELEMATIC SUPPORT FOR PATIENTES WITH SEVERE OBSTRUCTIVE SLEEP APNEA AND CPAP TREATMENT WITH ARE PROVIDED BAD FULFILLERS
EFECTO DE LA CPAP EN EL DETERIORO DE LA FUNCIÓN RENAL EN ESTADIOS PRECOCES DE ENFERMEDAD RENAL CRÓNICA (ESTUDIO RENAS)
EFICACIA DE LA VENTILACIÓN NO INVASIVA AJUSTADA AUTOMÁTICAMENTE EN EL SÍNDROME DE HIPOVENTILACIÓN OBESIDAD
NASAL VS ORONASAL NONINVASIVE VENTILATION IN CHRONIC HYPERCAPNIC PATIENTS: AN INDIVIDUAL DATA META-ANALYSIS. PROSPERO INTERNATIONAL PROJECT.
SMART LIVING HOMES - WHOLE INTERVENTIONS DEMONSTRATOR FOR PEOPLE AT HEALTH.
REGISTRO DE LA SOCIEDAD ESPAÑOLA DE NEUMOLOGÍA Y CIRUGÍA TORÁCICA DE PACIENTES CON COVID-19 (RECOVID)
EFECTIVIDAD A MEDIO Y LARGO PLAZO DE LA PRESIÓN POSITIVA DE LAS VÍAS RESPIRTARIAS EN SHO DESPUÉS DE UNA INSUFICIENCIA RESPIRATORIA HIPERCAPNICA AGUDA CRÓNICA. (SEGUNDA FASE Y RTC)
MID-TERM EFFECTIVENESS OF POSITIVE AIRWAY PRESSURE IN OHS AFTER AN ACUTE-ON-CHRONIC HYPERCAPNIC RESPIRATORY FAILURE. POST-ACUTE PICKWICK STUDY
ESTUDIO OBSERVACIONAL SOBRE LAS CARACTERÍSTICAS Y EVOLUCIÓN DE LOS PACIENTES DIAGNOSTICADOS DE ENFERMEDAD POR SARS-COV-2 EN EXTREMADURA (COVIEXTREM)

Publicaciones

CPAP titration failure is not equivalent to long-term CPAP treatment failure in patients with obesity hypoventilation syndrome: a case series.
Obesity hypoventilation syndrome.
Long-term clinical effectiveness of continuous positiveairway pressure therapy versus non-invasive ventilation therapy in patients withobesity hypoventilation syndrome: a multicentre, open-label, randomised controlled trial.
Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial.
Noninvasive Ventilation versus CPAP as Initial Treatment of Obesity Hypoventilation Syndrome.
Good long- term adherence to continuous positive airway pressure therapy in patients with resistant hypertension and sleep apnea.
Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline.
Biomarker panel in sleep apnea patients after an acute coronary event.
Prevalence, Characteristics, and Association of Obstructive Sleep Apnea with Blood Pressure Control in Patients with Resistant Hypertension.
Factors associated with the changes from a resistant to a refractory phenotype in hypertensive patients: a Pragmatic Longitudinal Study.
Effect of continuous positive airway pressure in patients with true refractory hypertension and sleep apnea: a post-hoc intention-to-treat analysis of the HIPARCO randomized clinical trial.
Continuous Positive Airway Pressure Treatment Does not Reduce Uric Acid Levels in OSA Women.
Normotensive patients with obstructive sleep apnoea: changes in 24-h ambulatory blood pressure monitoring with continuous positive airway pressure treatment.
Soluble PD-L1 is a potential biomarker of cutaneous melanoma aggressiveness and metastasis in obstructive sleep apnoea patients.
Proangiogenic factor midkine is increased in melanoma patients with sleep apnea and induces tumor cell proliferation.
Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma.
Effect of obstructive sleep apnoea and its treatment with continuous positive airway pressure on the prevalence of cardiovascular events in patients with acute coronary syndrome (ISAACC study): a randomised controlled trial.
Echocardiographic Changes with Positive Airway Pressure Therapy in Obesity Hypoventilation Syndrome. Long-Term Pickwick Randomized Controlled Clinical Trial.
Long-term Noninvasive Ventilation in Obesity Hypoventilation Syndrome Without Severe OSA: The Pickwick Randomized Controlled Trial.
The Effect of Sleep Apnea on Cardiovascular Events in Different Acute Coronary Syndrome Phenotypes.
Cost-effectiveness of positive airway pressure modalities in obesity hypoventilation syndrome with severe obstructive sleep apnoea.
Intra- and Inter-Physician Agreement in Therapeutic Decision for Sleep Apnea Syndrome.
Weight Loss Interventions as Treatment of Obesity Hypoventilation Syndrome. A Systematic Review.
The Role of Positive Airway Pressure Therapy in Adults with Obesity Hypoventilation Syndrome. A Systematic Review and Meta-Analysis.
The Effect of Hospital Discharge with Empiric Noninvasive Ventilation on Mortality in Hospitalized Patients with Obesity Hypoventilation Syndrome. An Individual Patient Data Meta-Analysis.
Clinical Practice Guideline Summary for Clinicians: Evaluation and Management of Obesity Hypoventilation Syndrome.
Effectiveness of different treatments in obesity hypoventilation syndrome.
Summary of Recommendations and Key Points of the Consensus of Spanish Scientific Societies (SEPAR, SEMICYUC, SEMES. SECIP, SENEO, SEDAR, SENP) on the Use of Non-Invasive Ventilation and High-Flow Oxygen Therapy with Nasal Cannulas in Adult, Pediatric, and Neonatal Patients With Severe Acute Respiratory Failure.
Abdominal obesity and myocardial infarction risk - We demonstrate the anthropometric and mathematical reasons that justify the association bias of the waist-to-hip ratio.
Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study.
Forum COPD Working Group Consensus on the Diagnosis, Treatment and Follow-Up of COPD.
Certified Smoking Cessation Units in Spain: High Potential for Detection of Undiagnosed Chronic Obstructive Pulmonary Disease and Profile of Newly Diagnosed Cases.
Primary versus Specialist Care for Obstructive Sleep Apnea: A Systematic Review and Individual Participant Data-Level Meta-Analysis.
Summary of Recommendations and Key Points of the Consensus of Spanish Scientific Societies (SEPAR, SEMICYUC, SEMES, SECIP, SENEO, SEDAR, SENP) on the Use of Non-Invasive Ventilation and High-Flow Oxygen Therapy with Nasal Cannulas in Adult, Pediatric, and Neonatal Patients With Severe Acute Respiratory Failure.
Nasal versus oronasal masks for home non-invasive ventilation in patients with chronic hypercapnia: a systematic review and individual participant data meta-analysis.
The HIPARCO-2 study: long-term effect of continuous positive airway pressure on blood pressure in patients with resistant hypertension: a multicenter prospective study.
Association of Obstructive Sleep Apnea with the Aging Process.
Reorganizing the respiratory high dependency unit for pandemics.
The value of open-source clinical science in pandemic response: lessons from ISARIC.
Diagnosis and Treatment of COPD Exacerbation Syndrome.
Obstructive sleep apnoea is related to melanoma aggressiveness through paraspeckle protein-1 upregulation.
Cost-Effectiveness of Once-Daily, Single-Inhaler COPD Triple Therapy in Spain: IMPACT Trial.
Spanish COPD Guidelines (GesEPOC) 2021 Update Diagnosis and Treatment of COPD Exacerbation Syndrome.
Spanish COPD Guidelines (GesEPOC) 2021: Updated Pharmacological treatment of stable COPD.
Risk factors associated with pulmonary hypertension in obesity hypoventilation syndrome.
Primary versus Specialist Care for Obstructive Sleep Apnea: A Systematic Review and Individual-Participant Data-Level Meta-Analysis.
Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome.
Long-Term Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Treatment on Blood Pressure in Patients with Acute Coronary Syndrome: A Clinical Trial.
Effect of CPAP treatment on BP in resistant hypertensive patients according to the BP dipping pattern and the presence of nocturnal hypertension.
Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study.
Consensus document on asthma and smoking of the Regional Asthma Forum of SEPAR.
Effectiveness of CPAP vs. Noninvasive Ventilation Based on Disease Severity in Obesity Hypoventilation Syndrome and Concomitant Severe Obstructive Sleep Apnea.
International Consensus Document on Obstructive Sleep Apnea.
Frequency and characteristics of asthma in smokers attending smoking cessation units in Spain.
Role of Sleep Apnea and Long-Term CPAP Treatment in the Prognosis of Patients With Melanoma: A Prospective Multicenter Study of 443 Patients.
Polysomnographic characterization of circadian blood pressure patterns in patients with obstructive sleep apnea.
Impact of treating obesity hypoventilation syndrome on body mass index.
Proteomic profiling for prediction of recurrent cardiovascular event in patients with acute coronary syndrome and obstructive sleep apnea: A post-hoc analysis from the ISAACC study.
Efficacy and Safety of Single-inhaler Triple Therapy Containing Dual Bronchodilator With Corticosteroids Compared to Monotherapy, Dual Therapy, or Open Triple Therapy in Moderate/Severe COPD: A Systematic Literature Review.
Documento de consenso sobre asma y tabaquismo del Foro Regional de Asma de SEPAR.
Clinical Practice Guideline of Spanish Society of Pneumology and Thoracic Surgery (SEPAR) on Pharmacological Treatment of Tobacco Dependence 2023.
Prevalence, Knowledge and Perceptions of Smoking and Tobacco Products and Vape Among SEPAR Members.
Procalcitonin and C-reactive protein to rule out early bacterial coinfection in COVID-19 critically ill patients.
Long-term effect of obstructive sleep apnoea management on blood pressure in patients with resistant hypertension: the SARAH study.
A blood microRNA classifier for the prediction of ICU mortality in COVID-19 patients: a multicenter validation study.
Everyone was Fooled, it Burns: Simple Diy Proof of the Falsity of Heat-Not-Burn Tobacco.
Efficacy and Safety of Single-inhaler Triple Therapy Containing Dual Bronchodilator With Corticosteroids Compared to Monotherapy, Dual Therapy, or Open Triple Therapy in Moderate/Severe COPD: A Systematic Literature Review.
High Follow-up Rate in Smokers With Diffuse Interstitial Lung Diseases: A Magnificent Opportunity for Tobacco Cessation Treatment?
The DESTINA Study: An Observational Cross-sectional Study to Evaluate Patient Satisfaction and Tolerability of Cytisine for Smoking Cessation in Spain